What are the taproots of estrangement among that breed of intellectual recognized as Jewish by accident of birth who have severed their religio-ethnic ties?

This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics committees, preceded by a brief introduction on the need for justification when using race as a variable or in defining a study population, the problem of exoticism, that distinctions pertain between race, ethnicity and ancestry, the problematic naming of races, and that race does not serve well (...) as a presumed biological construct in genetic research. (shrink)

Ineffability, method, and ontology, by G. Bergmann.--The glory and the misery of Ludwig Wittgenstein, by G. Bergmann.--Stenius on the Tractatus, by G. Bergmann.--Naming and saying, by W. Sellars.--The ontology of Wittgenstein's Tractatus, by E. D. Klemke.--Material properties in the Tractatus, by H. Hochberg.--Wittgenstein's pantheism: a new light on the ontology of the Tractatus, by N. Garver.--Science and metaphysics: a Wittgensteinian interpretation, by H. Petrie.--Wittgenstein on private languages, by C. L. Hardin.--Wittgenstein on private language, by N. Garver.--Wittgenstein and private languages, by (...) W. Todd.--The private-language argument, by H.-N. Castañeda.--Wittgenstein on privacy, by J. W. Cook.--"Forms of life" in Wittgenstein's Philosophical investigations, by J. F. M. Hunter.--Privacy and language, by M. S. Gram.--On language games and forms of life, by F. Zabeeh.--Wittgenstein on meaning and use, by J. F. M. Hunter.--Wittgenstein on phenomenalism, skepticism, and criteria, by A. Oldenquist.--Tractarian reflections on saying and showing, by D. W. Stampe.--Wittgenstein and logical necessity, by B. Stroud.--Negation and generality, by H. Hochberg.--Facts, possibilities, and essences in the Tractatus, by H. Hochberg.--Arithmetic and propositional form in Wittgenstein's Tractatus, by H. Hochberg.--Selected bibliography (p. 543-546). (shrink)

To show the importance of preparing historical editions as textual data first, while leaving presentation (whether in print or on the web) as a secondary down-stream task, this article identifies beneficial outcomes for research that can be achieved through computational analysis when such a corpus of textual data is at hand. With a focus on the deep intertextuality characteristic of the medieval scholastic corpus, it reviews three distinct methods for detecting different forms of textual relatedness within the corpus: n-gram intersections, (...) document embeddings, and convolution. In each case, special attention is given to how the availability of a domain specific knowledge graph helps us both properly prepare the corpus for analysis and visualize the results in ways that enhance research. Such results include observing trends in citation practices across different genres and sub-genres of the corpus, automatically grouping questions by similarity, and detecting sustained and uncited textual re-use. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

Background: Clinical investigation is a growing field employing increasing numbers of nurses. This has created a new specialty practice defined by aspects unique to nursing in a clinical research context: the objectives (to implement research protocols and advance science), setting (research facilities), and nature of the nurse–participant relationship. The clinical research nurse role may give rise to feelings of ethical conflict between aspects of protocol implementation and the duty of patient advocacy, a primary nursing responsibility. Little is known about whether (...) research nurses experience unique ethical challenges distinct from those experienced by nurses in traditional patient-care settings. Research objectives: The purpose of the study was to describe the nature of ethical challenges experienced by clinical research nurses within the context of their practice. Research design: The study utilized a qualitative descriptive design with individual interviews. Participants and research context: Participating nurses (N = 12) self-identified as having experienced ethical challenges during screening. The majority were Caucasian (90%), female (83%), and worked in outpatient settings (67%). Approximately 50% had > 10 years of research experience. Ethical considerations: The human subjects review board approved the study. Written informed consent was obtained. Findings: Predominant themes were revealed: (1) the inability to provide a probable good, or/do no harm, and (2) dual obligations (identity as a nurse vs a research nurse). The following patterns and subthemes emerged: conflicted allegiances between protocol implementation, needs of the participant, desire to advance science, and tension between the nurse–patient therapeutic relationship versus the research relationship. Discussion: Participants described ethical challenges specific to the research role. The issues are central to the nurse–participant relationship, patient advocacy, the nurse’s role in implementing protocols, and/or advancing science. Conclusion: Ethical challenges related to the specialized role of clinical research nurses were identified. More research is warranted to fully understand their nature and frequency and to identify support systems for resolution. (shrink)

A biography made up chiefly of excerpts from correspondence of Paul E. More, literary critic, editor of The Nation and teacher of classical and early Christian philosophy at Princeton. The central theme is More's religious development from Calvinism through humanism to a final great sympathy with Anglicanism.--R. C. N.

Emotional competence has an important influence on development in school. We hypothesized that reading and discussing children’s books with emotional content increases children’s emotional competence. To examine this assumption, we developed a literature-based intervention, named READING and FEELING, and tested it on 104 second and third graders in their after-school care center. Children who attended the same care center but did not participate in the emotion-centered literary program formed the control group ( n = 104). Our goal was to promote (...) emotional competence and to evaluate the effectiveness of the READING and FEELING program. Emotional competence variables were measured prior to the intervention and 9 weeks later, at the end of the program. Results revealed significant improvements in the emotional vocabulary, explicit emotional knowledge, and recognition of masked feelings. Regarding the treatment effect for detecting masked feelings, we found that boys benefited significantly more than girls. These findings underscore the assumption that children’s literature is an appropriate vehicle to support the development of emotional competence in middle childhood. (shrink)

While art is omnipresent in human history, the neural mechanisms of how we perceive, value and differentiate art has only begun to be explored. Functional magnetic resonance imaging studies suggested that art acts as secondary reward, involving brain activity in the ventral striatum and prefrontal cortices similar to primary rewards such as food. However, potential similarities or unique characteristics of art-related neuroscience remain elusive, also because of a lack of adequate experimental tools: the available collections of art stimuli often lack (...) standard image definitions and normative ratings. Therefore, we here provide a large set of well-characterized, novel art images for use as visual stimuli in psychological and neuroimaging research. The stimuli were created using a deep learning algorithm that applied different styles of popular paintings on ordinary animal, plant and object images which were drawn from established visual stimuli databases. The novel stimuli represent mundane items with artistic properties with proposed reduced dimensionality and complexity compared to paintings. In total, 2,332 novel stimuli are available open access as “art.pics” database at https://osf.io/BTWNQ/ with standard image characteristics that are comparable to other common visual stimuli material in terms of size, variable color distribution, complexity, intensity and valence, measured by image software analysis and by ratings derived from a human experimental validation study [n = 1,296, age 30.2 ± 8.8 y.o.]. The experimental validation study further showed that the art.pics elicit a broad and significantly different variation in subjective value ratings as well as in recognizability, arousal and valence across different art styles and categories. Researchers are encouraged to study the perception, processing and valuation of art images based on the art.pics database which also enables real reward remuneration of the rated stimuli and a direct comparison to other rewards from e.g., food or money.Key Messages: We provide an open access, validated and large set of novel stimuli of standardized art images including normative rating data to be used for experimental research. Reward remuneration in experimental settings can be easily implemented for the art.pics by e.g., handing out the stimuli to the participants, as done in the presented validation task. Experimental validation showed that the art.pics’ images elicit a broad and significantly different variation in subjective value ratings across different art styles and categories, while size, color and complexity characteristics remained comparable to other visual stimuli databases. (shrink)

We show that all QE rings of prime power characteristic are constructed in a straightforward way out of three components: a filtered Boolean power of a finite field, a nilpotent Jacobson radical, and the ring Z p n or the Witt ring W 2 (F 4 ) (which is the characteristic four analogue of the Galois field with four elements).

In lieu of an abstract, here is a brief excerpt of the content:Plotinus and the Parmenz'des B. DARRELL JACKSON IN 1928 E. R. DODDSARGUED that the first two hypotheses of Plato's Parmenides are the primary source of Plotinus' doctrines of the One and of Nous. I Dodds' main evidence was a list of parallels between the Parmenides and the Enneads? He argued further that the Neoplatonic interpretation of the Parmenides as positive metaphysics was neo-Pythagorean in origin. Several Plotinus scholars have (...) accepted and extended Dodds' view of the importance of the Parmenides for Plotinus. This group includes ]~mile Br6hier, ~ A. H. Armstrong, 4 Hans-Rudolf Schwyzer, 5 and Paul Henry. n But Dodds' position is by no means universally accepted. Elmer O'Brien has recently argued that the Plotinian One was derived ultimately from Philo and mediated to Plotinus through Albinus and Numenius. 7 He says that Dodds' case, though good, is not convincing. It. A. Wolfson has been the great advocate of the Philonic origin of Plotinus' views. According to Wolfson, the doctrines attributed by Plotinus to Plato are not Plato's but mainly Philo's. 8 Others see Plotinus in varying degrees of dependence upon Plato. Philip Merlan holds that Plotinus is more in debt to the immediate successors of Plato and to Aristotle's interpretation of Plato than to the Platonic writings themselves. 9 C. J. de Vogel sees Plotinus as dependent upon Plato for a hierarchy of being which was accepted and elaborated by various middle Platonists and Gnostics. 1~According to de Vogel, the Parmenides wus not importan% in this hierarchy tradition, n In this article I shall re-examine Dodds' position. I believe the case for Plotinus' dependence upon the Parmenides can be strengthened. I shall try to do this by examining the systematic relation of Plotinus' thought to the Parmenides. Dodds x"The Parmenides of Plato and the Origin of the Neoplatonic 'One'," The Classical Quarterly, XXII (1928), 129-142. 2Ibid., 132 f. *In the introductions to Enneads V.3 (esp. pp. 43 f., 46 f.), V.5 (pp. 87 ft.), VI.4-5 (pp. 161163,165-168),and VI.7 (pp. 49, 60) in his Bud~ edition and translation of the Enneads (Paris, 1931-38). 4The Architecture of the Intelligible Universe in the Philosophy of Plotinus (Cambridge, at the University Press: 1940), pp. 14-28. In his article "Plotinos", Vol. 21, pt. 1 of Paulys Real-Encyclopgdie der Klassischen Altertumswissenschaft, 1951, cols. 552-554. eIntroduction to the second edition of Stephen MacKenna's translation of the Ennead.~ (New York: Pantheon Books Inc., n. d.), pp. xli-xliv. Elmer O'Brien (ed. and trans.), The Essential Plotinus (New York: Mentor, 1964),p. 15. 8"Albinus and Plotinus on Divine Attributes," Harvard Theological Review, XXXXV (1952), 115. 9From Platonism to Neoplatonism (2n ed. rev.; The Hague: Martinus Nijhoff, 1960). 10"On the Neoplatonic Character of Platonism and the Platonic Character of Neoplatonism," Mind, LXIII (1953), 43-64. 11Ibid., 58. [3]5] 316 HISTORY OF PHILOSOPHY considered only parallel terminology. I shall in addition look at parallel argumentation and conclusions. Furthermore, since Dodds accounts only for Plotinus' first two hypostases, I shall consider the relation of the third hypostasis (soul) to the Parmenides. My primary interest is not the source of Plotinus' interpretation of the Parmenides but the way he carries that interpretation out. TM The former issue has often been focal in the literature on this subject. ~8It is certain thay many of the ideas used by Plotinus were already in circulation. But it is equally certain that in his combination of these ideas of a hierarchy, of transcendence, etc., Plotinus is original. I shall argue that this originality of combination is largely determined by an interpretation of the Parmenides. I should add that I am not concerned with whether Plotinus' interpretation is correct. ~4 In the following pages I shall attempt to show three things: (1) how Plotinus explicitly interprets the Parmenides, (2) to what extent he draws upon the language of the Parmenides, and (3) to what extent Plotinus' system may be understood by its relation to the Parmenides. I. Plotinus' Interpretation of the Parmenides The obvious place to begin an analysis of Plotinus' relation to the Parmenides is Enneads V... (shrink)

This addition—hence the title Mantissa—to the rich vein of information about Constantine Samuel Rafinesque is in fact a supplement to Charles Boewe's own revised and enlarged edition of Thomas J. Fitzpatrick's book Rafinesque .The details of the peripatetic life of Rafinesque, one of America's most original yet undisciplined naturalists, are too well known to bear repeating here. Suffice it to say that because of the vicissitudes of his life—his perpetual wandering between and within Europe and frontier America, his impecunious circumstances (...) that forced him to find different ways of making a living—finding and identifying his publications is a bibliographer's nightmare. Even now, more than 160 years after his death and with the benefit of serious studies by Fitzpatrick and Boewe, as well as by Richard E. Call and Elmer D. Merrill, among others, we can only approximate the number of his publications, including both original titles and republications. Probably we will never have a complete list of Rafinesque's publications because he published regularly in newspapers, broadsides, sales catalogues, privately printed journals, and other ephemera that are infrequently archived. Even his own references to “published” works cannot be trusted as, to him, this term included papers that he sent to journals but were never published. On the other hand, Rafinesque complained to one correspondent that he never knew whether some of these manuscripts were ever published or he learned only years later that they had been. The total number has been estimated at about a thousand, but, as Boewe points out, this number is based on Fitzpatrick's faulty numbering system in which each version of a paper or volume of a multivolume work was given a number. Thus Fitzpatrick's system, continued by Boewe, represents serial numbers, not individual titles. Rafinesque's own estimate was 220, a number Boewe now thinks is a reasonable guess.The Mantissa is an important addition to Rafinesquiana. It lists twenty hitherto‐unrecorded publications by Rafinesque, thirty‐three new translations or reprints, and more than two hundred newly listed secondary references. For the first time we have a list of every manuscript letter written by Rafinesque that is known to exist, and Boewe provides a documented discussion of Rafinesque publications still remaining to be discovered. Several titles known to me, however, are missing from Mantissa, but Boewe's book represents a learned guide for the next scholar willing to take up the challenge and carry on the search. The newly listed manuscript letters will doubtless be particularly helpful in providing leads to undiscovered publications and other facets of Rafinesque's still not completely understood life. Among his correspondents were fellow naturalists such as John James Audubon, Joseph Banks, Benjamin Barton, Charles Bonaparte, Alexandre Brongniart, Augustin de Candolle, Georges Cuvier, Amos Eaton, Asa Gray, William Jackson Hooker, Muhlenberg, Ord, Paolo Savi, James Edward Smith, William Swainson, and John Torrey, as well as prominent leaders of the day, including John Adams, De Witt Clinton, Eleuthère Irénée du Pont, George IV, Thomas Jefferson, and Joel Roberts Poinsett. A total of 346 letters are listed.More important, Boewe has given us the benefit of his many years of scholarly searching and thinking about Rafinesque in his discussions entitled “Hints about Unlisted Titles,” “Letters as a Source of Leads,” and “Hints in Publications.” We learn, for example, that Rafinesque signed some of his papers simply as “Constantine” or “Linneus.” The Mantissa makes it abundantly clear why arriving at a complete account of Rafinesque's writings is an elusive goal, but Boewe shows us that the attempt still offers an exciting trail to follow. (shrink)

Explores intellectual and philosophical evolution of German philosopher Martin Heidegger, focusing on period after World War II. Analyzes how Heidegger s ideas, particularly his notion of being, influenced and were influenced by postwar context, including confrontation with Nazism and emergence of new philosophical currents. Argues that Heidegger s work offers relevant insights for contemporary philosophical debates and calls for a critical dialogue with his legacy. Discusses Heidegger s philosophy in the context of French and German philosophical schools, highlighting relevance of (...) his ideas and impact they had on contemporary philosophy. (shrink)

El texto aquí presentado tiene el propósito de poner en diálogo la filosofía de Friedrich Schelling, específicamente las tres versiones de Las edades del mundo (1811, 1813, 1815), con el trabajo de Gilles Deleuze: Diferencia y repetición (1968) alrededor de los conceptos de disyunción y Diferencia. Su tarea escala en una doble evaluación complementaria. En principio, pone en conexión el concepto de síntesis disyuntiva de Deleuze con la doctrina de las potencias de Schelling. Posteriormente, a partir de entender la propia (...) disyunción schelling- niana, veremos cómo actuaría de manera implicatoria sobre las formulaciones de la ontología univocista del propio Deleuze; tensando conceptos como el de eterno retorno e intensidad, para argumentar una comparación entre los dos textos escogidos. (shrink)

Decision-making capacityDecision-making capacity for pediatric patients can be difficult to determine and is influenced by a myriad of developmental considerations. This chapter begins with a discussion concerning the nature of decision-makingDecision-making and what constitutes competency. The “rule of sevensRule of sevens” frameworkFramework is then used to explicate pertinent developmental milestonesMilestones for children, dividing pediatric developmentDevelopment into 0–7, 7–14, and 14+ years of age. In particular, the authors highlight the most important cognitiveCognitive, socialSocial, andSocial emotionalemotionalEmotional considerations in each of these periods (...) and how they pertain to a child’s ability to make important medical decisions. (shrink)

Using mobile health research as an extended example, this article provides an overview of when the Common Rule “applies” to a variety of activities, what might be meant when one says that the Common Rule does or does not “apply,” the extent to which these different meanings of “apply” matter, and, when the Common Rule does apply, how it applies.

Эта книга поможет пролить свет на метафизическое осмысление философии истории, подведет к более глубокому пониманию сущности добра и зла, предложенному известным русским философом и мыслителем Н. Ф. Федоровым.